Spain's Interior Ministry says 11 police officers have been injured fulfilling judicial orders to prevent the referendum on independence in northeastern Catalonia from taking place.
The ministry tweeted that the injured Sunday included nine National Police officers and two Civil Guard agents.
Police battled with pro-referendum supporters in the streets of Barcelona on Sunday, baton charging them and firing rubber bullets. Hundreds of people were reported injured.
The ministry posted a video on its Twitter account showing Civil Guard officers jumping into two police vehicles to flee a stone-throwing mob in the town of Sant Carles de la Rapita.
Catalonia's government spokesman says 337 people have been injured, some seriously, during the police crackdown Sunday on a banned referendum on breaking away from Spain.
Jordi Turull said he couldn't disclose more details about the wounded out of respect to their relatives.
Police fired rubber bullets near at least one Barcelona polling station, and have clashed with protesters throughout Catalonia.
The regional government's spokesman, Jordi Turull, blamed the violence directly on Spanish Prime Minister Mariano Rajoy and Interior Minister Juan Ignacio Zoido.
Turull said that actions by Spanish National Police and Civil Guard forces on Sunday were politically motivated and showed "a clear motivation to harm citizens.''
Catalan international affairs director, Raul Romeva, said that regional authorities would appeal to European authorities for Rajoy's governments' violations of human rights.
Spanish deputy prime minister says Spanish police have intervened with ``firmness and proportionality'' against the Catalan vote on secession.
Soraya Saenz de Santamaria said Sunday Spanish authorities acted in a professional and proportional way, and that they weren't going after voters, but referendum material.
She accused the Catalan government that is trying to hold the referendum of behaving with absolute irresponsibility.
She said, "There hasn't been a referendum or the semblance of one."